If you want to target specific Uniques and Mythic Uniques in Diablo 4, farming specific bosses is the most efficient method. This guide will give you complete details about every boss in the game along with their drop tables as well as the means to summon them. After reading this guide, you will be able to improve the quality of your loot and even alter your build for optimal performance.

• Season 6 Changes and Further Developments
• Varshan: Drops and Location
• Grigoire: Drops and Location
• Lord Zir: Drops and Location
• Beast in Ice: Drops and Location
• Duriel: Drops and Location
• Andariel: Drops and Location
• Infernal Hordes: Drops and Location
• Mythic Uniques: A New Tier of Power
• Final Thoughts

↖ Season 6 Changes and Further Developments

As for Season 6, Blizzard shifted the roadmap of the games difficulty with the introduction of new systems. The old World Tiers have been remapped into new structures called Torment Levels. The first of these levels is accessible after accomplishing the Grube dungeon. Starting from Torment Level 1, all bosses are available and the quantity and quality of the loot grows with the higher Torment Level. Moreover, the materials for summoning bosses are now obtainable from the Underworld of Kurast, Helltide events, and even the Whispering Tree.

Each boss, their locations, materials for summoning, and of course, their unique loot are all explained in detail above.

↖ Varshan: Drops and Location

Varshan is found and can be fought starting at Torment level 1 right by the Whispering Tree in his Malignant Lair. He has tasks that reward body pieces necessary to summon Varshan. These can be acquired during Helltide events as well, so make sure to keep an eye open for them. Uniques, a mount trophy, and other items are rewarded for defeating Varshan.

Summoning Requirements:

To summon Varshan on any of the torment levels, you will need to have in possession 4 malignant hearts.

Loot Table:

Farmable Uniques drops are specific for Varshan which can be used to build further optimizations.

↖ Grigoire: Drops and Location

Grigoire can be summoned starting at the Dry Steppes located in the Hall of Atonement in Torment level 1. Players need to acquire Living Steel that is dropped by Treasure goblins, Helltide events, Underworld of Kurast, etc. Grigoire drops mount armor for enhancing looks in addition to Uniques.

Summoning Requirements:

12 Living steel is required to summon Grigoire on any torment level, which will allow him to be summoned.

Loot Table:

For some endgame builds, Grigioe drops Uniques that are extremely important.

↖ Lord Zir: Drops and Location

You can find Lord Zir in Kyovashad, eastern region Darkened Path located in Seat of the Ancient. To summon Lord Zir you must have Exquisite Blood which comes from many sources including Treasure Goblins, world bosses, Helltide events and Underworld of Kurast. Along with Uniques, Zir bestows players with a cosmetic headpiece.

Summoning Requirements:

12 Bottles of Exquisite Blood are required to summon Zir at any Torment Level.

Loot Table:

Advanced players build specific Uniques that Lord Zir drops as Uniques are highly saught after.

↖ Beast in Ice: Drops and Location

The Beast in Ice is found in the southwest region of Kyovashad in the dungeon Glacial Rift. Players can summon this boss starting from Torment Level 1 using Distilled Desire, which can be extracted from Nightmare Dungeons. Players will gain Uniques and mount trophies upon defeating the Beast.

Summoning Requirements:

Requires 12 Bottles of Distilled Desire to summon the Beast at any level.

Loot Table:

The Beast in Ice must be defeated if you're looking to add powerful Uniques to an Uniques arsenal that complement an increased number of play styles.

↖ Duriel: Drops and Location

For Duriel to appear, you must go to the Gaping Rift just south east of Gea Kul. Once there, he can be summoned using Slimy Eggs and Shards of Torment which can be obtained from Varshan, Grigoire, world bosses, Treasure Goblins, and Helltide events. Apart from his Uniques, Duriel also drops a unique mount.

Summoning Requirements:

Players will need to procure 2 Slimy Eggs and 2 Shards of Torment at any Torment Level to summon Duriel.

Loot Table:

Losable Uniques rare for high-level builds are on Duriel's loot table.

↖ Andariel: Drops and Location

Andariel is located in the Hall of the Hanged Man in Kehjistan near the Tarsarak waypoint. Players are required to possess Sandscorched Shackles and Needle-Pierced Dolls, both of which can be dropped from Zir, the Beast in Ice, and some Helltide events. He shares some of the similarities in loot from Duriel, such as Uniques and a mount.

Summoning Requirements:

Andariel can be summoned by acquiring 2 Sandscorched Shackles and 2 Needle-Pierced Dolls at any Torment Level.

Loot Table:

Powerful Uniques are dropped by Andariel, and some of his loot has overlap with Duriel's.

↖ Infernal Hordes: Drops and Location

Infernal Hordes is the newly-added feature in Season 5, which combines an endgame activity with battles. Fights against tons of waves of monsters with thrilling fights against three bosses. To gain access to this feature players need to acquire Infernal Compasses. These compasses can be obtained by participating in Helltide Events or at the Grube Dungeon once the Torment Level 1 is achieved.

Loot Table:

There is always a chance of farming special pieces in the Uniques at Infernal Hordes although their drops are hardly achievable within the warfare battles.

↖ Mythic Uniques: A New Tier of Power

After the Season 6, every single boss within the game has a chance to drop highly Mythic uniques along with those highly rated items which are very difficult to acquire. Mythic Uniques are dropped during a player's endgame activities such as those in the vessels of hatred expansion's Kurast Underworld. Different builds require Mythic Uniques and players can gain power by utilizing them in the game which makes them integral of sorts.

↖ Final Thoughts

Now that Season 7 of Diablo 4 is here this guide quickly touches on the unattainable farming Uniques and Mythic uniques that will build up your character. Fulfilling these requirements benefits the players by crafting amazing builds towards the end of the game. If you want to get the maximum output from your farming diagnosis, learn the mechanics while you kill bosses or roam through the Infernal Hordes.